Topaz has been growing businesses for over 20 years, including two of her own. She started working with start-up companies in Seattle, USA in 2000, as a founder, CEO, venture capitalist and finally as an investor. Her experience spans a number of industries, including IT, e-commerce, bio-engineering, and med-tech.

In addition to being Chair of SBE Australia (a NFP Accelerator for women-led companies delivering the world class Springboard Accelerator) since 2014, Topaz is a Director of Cicada Innovations (NSWs Deep-Tech incubator), is on the Advisory Council to the Minister of Research & Innovation in Alberta, Canada (ARIAC), and is a Commercialisation Advisor to the Accelerating Commercialisation Grant Program. She is immediate past Chair of PAFTec Pty Ltd, a respiratory protection device company, and has been a Director on the Telstra Industry Advisory Board.